Self-renewal equality in pancreas homeostasis, regeneration, and cancer
Chiara Falcomatà , Dieter Saur
Cell Rep. 2021 Dec 14;37(11):110135. doi: 10.1016/j.celrep.2021.110135.
Abstract:
Two studies by Lodestijn et al. in Cell Stem Cell and Cell Reports reveal a lack of stem cell hierarchies in acinar cell-derived tissue renewal and host instructed clonogenic growth of pancreatic cancer, thereby elucidating determinants of pancreas regeneration and cancer.