Dieter Saur studied medicine in Munich and obtained his doctorate in gastroenterology at TUM’s university hospital, graduating summa cum laude and winning TUM’s doctoral award. His doctoral thesis and postdoctoral qualification (2006) investigated neuronal control of the intestine, i.e. “brain-gut” function. A clinician and a researcher in one person, Saur established a new focus on tumor diseases of the gastrointestinal tract in 2002. The use of new endoscopic imaging procedures for early detection of gastrointestinal tumors and the development of novel therapeutic strategies for tumor subtypes are key topics of his research. A consultant of internal medicine specializing in gastroenterology since 2007 and a professor since 2013, Saur has accumulated a range of awards and grants along the way – most recently the prestigious Consolidator Grant from the European Research Council (ERC) for his work in pancreatic cancer.
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Colorectal cancer research: inflammation in oncogene-induced intestinal tumourigenesis
I did my Bachelor’s degree in Biology (2010) and my Master’s study in Molecular Cell and Developmental Biology (2011) at the Leopold-Franzens-University (LFU) of Innsbruck (Austria). During my Master’s, I went for a free-mover semester and research stay at the Swiss Federal Institute of Technology (ETH) Zurich (Switzerland). After I completed my Master’s degree, I started a PhD at the Medical University of Innsbruck (MUI) and continued my PhD in 2013 at the University of Cambridge (Fitzwilliam College; United Kingdom) in the lab of Prof. Arthur Kaser, where I graduated in 2016 as PhD in Medicine. After graduation, I accepted the kind offer of Prof. Saur to join his lab as a postdoctoral research fellow at the Technical University of Munich (TUM, Klinikum rechts der Isar). Since January 2019 I occupy the position of a Junior Group Leader in the lab of Prof. Saur.
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PhD graduate students
Multi-omics characterisation of the PDAC tumour microenvironment
I did my first Master’s degree in medical Biotechnology (2019) at the university of Perugia (Italy) and my second Master’s study in Bioinformatics (2021) at the University of Bologna (Italy). During my second Master’s, I went for an Erasmus internship at Theis Lab at the institute of computational biology (ICB Helmholtz centre Munich) where I worked on my master thesis. As a PhD student in the Saur Lab, I am currently analysing multi-omics data with a focus on single cell technologies to decipher the tumour micro environment composition in PDAC and the complex communication network between cancer cells and the immune system.
Multi-modal spatial-omics analysis
(i.e. histology whole slide images & spatial transcriptomics). Integrating spatial gene expression and pancreatic tumour morphology (multi-modal spatial-omics analysis) to predict tumour subtypes and therapeutic vulnerabilities
I am a first year PhD Candidate at Saur Lab (TranslaTUM), Peng Lab (Helmholtz Munich). Before joining as a doctoral candidate, I was a researcher at Boston University, School of Medicine (BUSM), USA, working on developing image biomarkers of lung squamous premalignant progression. I got my master’s degree in computer science from Rutgers University, USA. My master’s thesis involved developing methods for automatic cardiac segmentation using multi-modal data. My research interests are specifically focused towards deep learning and medical image analysis. I aim to become a research scientist bridging the gap between state of the art academic research and it’s huge translational potential in biomedical industry.
Tumor microenvironment in pancreatic ductal adenocarcinoma
Single-cell RNA sequencing
Tumor microenvironment in PDAC
KRAS-dependency and heterogeneity in PDAC
I completed my BSc studies in Microbiology at the University of Ljubljana, Slovenia, in 2018, and afterwards MSc in Genetics and molecular biosciences at the University of Helsinki, Finland, in 2020. I continued my research for one year at the National Institute of Chemistry, Slovenia, where I worked in the field of immunology and synthetic biology. Since 2021 I am a PhD student in Saur lab, where I am investigating KRAS dependency and heterogeneity of PDAC tumors, using transgenic mouse models.
Investigation of combinatorial treatment strategies in pancreatic ductal adenocarcinoma
Born and raised in beautiful Bucharest, Romania, I started studying medicine at the LMU in 2015 and joined our research group in 2019. When I’m not running around the lab doing western blots, taking care of my cells or preparing for exams – I love to be in the mountains, listen to as much live music as I can, travel and generally keep busy.
CRISPRa screening in prancreatic ductal adenocarcinoma
I studied preclinical medicine at the Ludwig-Maximilians-University (LMU) Munich from 2015-2017 and have been continuing my clinical studies at the Technical University of Munich (TUM) since 2017. After finishing the preclinical part of my course, I started studying B.A. Philosophy at the LMU in 2017, parallel to my medical studies. In April 2020 I joined the Saur lab to work on my MD thesis in translational medicine (Dr. med. sci) on CRISPRa screening in PDAC.
I am from Colombia and came to Germany for my studies in pharmaceutical bioprocess engineering (Pharmazeutische Bioprozesstechnik) that started in October 2019. One of my goals is to collaborate on the investigation and cure of diseases, which is why August 2019 I joined our research group. Appart from my studies I like to read and see new places in this beautiful county.